

Paperback: 387 pages
Publisher: Prometheus Books; 1 edition (June 11, 2013)
Language: English
ISBN-10: 1616147237
ISBN-13: 978-1616147235
Product Dimensions: 6 x 1 x 9 inches
Shipping Weight: 15.2 ounces (View shipping rates and policies)
Average Customer Review: 4.8 out of 5 stars See all reviews (12 customer reviews)
Best Sellers Rank: #219,496 in Books (See Top 100 in Books) #23 in Books > Health, Fitness & Dieting > Men's Health > Prostate Health #64 in Books > Health, Fitness & Dieting > Diseases & Physical Ailments > Cancer > Breast Cancer #109 in Books > Health, Fitness & Dieting > Diseases & Physical Ailments > Alzheimer's Disease

Article Written by Carol Petersen, RPh, CNP – Women’s International PharmacyThere is no shortage of information and opinions concerning hormone treatments or the "best" way to test for hormone deficiencies, not to mention how to use hormones or confirm if a hormone intervention is working. However, upon reading Dr. Edward Friedman's new book, The New Testosterone Treatment: How You and Your Doctor Can Fight Breast Cancer, Prostate Cancer, and Alzheimer's, it occurred to me that hormone receptors are really THE thing we should examine. Regardless of the testing method, the specific hormone, or its intended result, all hormone action occurs at the receptor sites.What are Receptors?Receptors are protein structures designed to snag passing hormones. Receptors for hormones that poke through the cell membrane are called membrane receptors. Other receptors are inside the cell (intracellular receptors) in the cytosol, and more receptors are in the cell nucleus. The number of receptors is not stagnant, and varies according to nutrients and the environment.Once a receptor captures a hormone, that cell receives instructions for an action, such as cell replication, manufacturing other proteins, moderating cell activity, and programming abnormal cell death. A single hormone can produce action within minutes of binding. Receptors manipulate the cell's action by upregulating or down-regulating the production of proteins.Hormones Have AffinitiesConventional practitioners insist that as long as a hormone receptor receives a hormone—whether it is identical to the human hormone or not—all hormones and hormone-like substances should be considered equal.
Bioidentical Hormones and Alzheimer's (Carol Petersen - Women's International Pharmacy)Just like “Wonderbread helps build strong bodies 12 ways” Dr. Edward. Friedman , in his book “The New Testosterone Treatment: How You and Your Doctor Can Fight Breast Cancer, Prostate Cancer, and Alzheimer's “ writes how bioidentical hormones help prevent Alzheimer’s disease in 9 different and documented ways.Two abnormalities commonly associated with Alzheimer’s are beta amyloid plaques between neurons in the brain and neurofibrillary tangles within the neurons. The tangles are composed of hyperphosphorylated tau protein which eventually kills the neuron. Impaired glucose metabolism in the brain and poor blood circulation to the brain are also associated with Alzheimer’s. Alzheimer’s disease destroys brain function and is ultimately fatal.1. Apolipoprotein Ee4 is a genetic mutation which hinders beta amyloid excretion from the brain. Vitamin D3 increases the excretion of beta amyloid from the brain.2. Beta amyloid secretion is impaired by both testosterone and estradiol. Cycling with progesterone also enhances this impairment ability of estradiol.3. Beta amyloid is a peptide created from 40 or 42 amino acids. An increased ratio of the 42 amino acid structure over the 40 is associated with Alzheimer’s. This ratio is decreased by testosterone.4. Alpha secretase is an enzyme that prevents production of beta amyloid. Both estradiol and testosterone increase alpha secretase activity.5. Beta secretase is an enzyme that increases the production of beta amyloid. Estradiol and testosterone decrease beta secretase.6. The enzyme neprilysin degrades beta amyloid. Testosterone and estradiol increase neprilysin activity.7.
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