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Brain Tumors (Contemporary Cancer Research)

Exciting new developments and discoveries of the last two decades are beginning to shed light on the complex biology of brain tumors and are advancing our understa- ing of the cellular and molecular processes involved in their initiation, progression, and clinical and biological behavior. The disease process in brain tumors is quite complex and the resulting tumors are characterized by a high degree of biological and clinical diversity. Thus, despite the advances of the last two decades, prognosis for patients with malignant brain tumors remains abysmal. Significant progress in the diagnosis, treatment and, ultimately, prevention of these tumors will require both the timely h- nessing of the advances in basic and clinical brain tumor research, and a continuing concerted effort at increasing our understanding of brain tumor biology, in particular, the molecular genetic changes and perturbations of cellular pathways involved in brain oncogenesis and which drive the biological and clinical behavior of the tumors. Brain tumor diagnosis and prognosis, which is still largely based on histopathology and other clinical criteria, will, in the future, acquire a significant molecular component, with the incorporation of knowledge of genes that are mutated, over-expressed, deleted, silenced, or functionally altered in the tumors. Treatment strategies for brain tumors, rather than being empirical, will be rationally developed based on an understanding of the cellular and molecular mechanisms and targets that have been activated, suppressed, or otherwise altered.

Series: Contemporary Cancer Research

Hardcover: 393 pages

Publisher: Humana Press; 2005 edition (October 1, 2005)

Language: English

ISBN-10: 1588290425

ISBN-13: 978-1588290427

Product Dimensions: 7 x 0.9 x 10 inches

Shipping Weight: 2.2 pounds (View shipping rates and policies)

Average Customer Review: 4.0 out of 5 stars  See all reviews (1 customer review)

Best Sellers Rank: #4,197,355 in Books (See Top 100 in Books) #81 in Books > Health, Fitness & Dieting > Diseases & Physical Ailments > Cancer > Brain Cancer #4006 in Books > Medical Books > Medicine > Internal Medicine > Oncology #11704 in Books > Medical Books > Medicine > Internal Medicine > Neurology

This book is one I will keep until I am in remission for a very long time. It is more to the technichal side, but very informative. For me to purchase my next book specific to Glia Cells and the greater function they have than nuerons! Good book for you shelf of self inquiry! I wish anyone going through brain cancer or any cancer would read the books and know how very far we are away from understanding things like the brain!

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